The home for Tough Tech
Our residents are
Tough Tech
companies building solutions for a healthier, more productive, and more sustainable world.
Tough Tech
Tough Tech is transformational science and engineering that solves the world’s most important challenges.
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MacroCycle's pilot plant at 750 Main, poised to upcycle up to 200,000 plastic bottles annually.
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The Engine Accelerator 750 fabrication space.
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Axoft: The ElastrodeTM: A soft and high-bandwidth neural interface.
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Hyfe's: understanding impacts of feed variability on bioprocess.
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HyperLight's 110 GHz modulator.
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Commonwealth Fusion Systems' magnet factory in Devens.
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Via Separations pilot for industrial processes.
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Biobot's Lab. (credits: The Tech Interactive).
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One of Atlantic Quantum's test and measurement laboratories located in Cambridge.
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Cellbricks Therapeutics and Mayor of Berlin cut the ribbon for a transatlantic launch at The Engine.
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Tough Tech Week 2024 brought Activate Demo Day to The Engine!
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Build Here
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220,000ft² of convergent wet lab, engineering, and office space with the equipment to build Tough Tech — fully managed by our expert team.
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Learn Here
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Our programming addresses the complex challenges of commercializing disruptive technologies, making Tough Tech entrepreneurship more accessible.
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Connect Here
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Our thriving ecosystem brings together essential Tough Tech stakeholders: Entrepreneurs, Academia, Government, Corporates, and Capital Providers.
Highlights
“The Engine is a hub for Tough Tech that fills the gaps in resources, infrastructure, and institutional support for founders on their journey from research breakthroughs to commercial impact.”
Emily Knight CEO & President, The Engine ![]()
- Infrastructure
- 227,000 sq feet of fully-managed lab and engineering space
- Resident Services
- 32 Staff Members Available to Extend Your Team
- Resident Companies
- 98 Resident Companies
- Resident Companies
- 19 Tough Tech Industries
- Whiteboard
- 25 Participating Institutions
- NSF Builder Platform
- 9 Regional Innovation Ecosystems
- Partners
- 15 Corporate Partners
